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Do not take this medication at or while you are still in bed. It may not be absorbed and you may have side effects. No evidence of metabolism of alendronate. Sedentary lifestyle. People who spend a lot of time sitting have a higher risk of osteoporosis than do those who are more active. Any weight-bearing exercise and activities that promote balance and good posture are beneficial for your bones, but walking, running, jumping, dancing and weightlifting seem particularly helpful. Commonwealth Department of Health and Family Services, Australian National Consensus Conference 1996. The prevention and management of osteoporosis: consensus statement. Med J Austral.

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Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Your story is well heeded and I really hope you will get some good help now. Do you have more questions? Make a list of all medications, vitamins and supplements that you're currently taking or have taken in the past. It's especially helpful if you record the type and dose of calcium and vitamin D supplements, because many different preparations are available. If you're not sure what information your doctor might need, take the bottles with you. My OBGYN may NOT be as on top of this as a rheumatologist or osteo doc.

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Gamble and Sanofi -- appears in the current online issue of the journal International. Do not take these for at least 30 minutes preferably 1 to 2 hours after taking alendronate. Roux C, Oriente P, Laan R et al. Randomized trial of effect of cyclical etidronate in the prevention of corticosteroid-induced bone loss. J Clin Endocrinol Metab. Certain supplements and foods may also interfere with the absorption of this medication, such as calcium or iron supplements, vitamins with minerals, antacids, olestra, dairy products such as milk, yogurt mineral water, coffee, tea, and calcium-enriched juice. Do not take these products for at least 30 minutes preferably 1 to 2 hours after taking this medication.

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What is the dosage for alendronate? Vitamin D improves your body's ability to absorb calcium and improves bone health in other ways. People can get adequate amounts of vitamin D from sunlight, but this may not be a good source if you live in a high latitude, if you're housebound, or if you regularly use sunscreen or avoid the sun entirely because of the risk of skin cancer. If you think you may have a serious medical problem, seek immediate medical attention.

Do you think you get enough calcium?

Discuss the risks and benefits with your doctor. Center for Drug Evaluation and Research, Food and Drug Administration. Tell your doctor or dentist that you take Fosamax Plus D before you receive any medical or dental care, emergency care, or surgery. Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Maricic M. Early prevention vs late treatment for osteoporosis. Arch Intern Med. Bone thinning occurs as part of aging. Bone Health in Adults as a National Public Health Priority.

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Fosamax is available in a tablet or oral liquid form. Fosamax is to be used only by the patient for whom it is prescribed. Do not share it with other people. NSAIDs can raise the risk of or strokes. Treatment recommendations are often based on an estimate of your risk of breaking a bone in the next 10 years using information such as the bone density test. If the risk is not high, treatment might not include medication and might focus instead on modifying risk factors for bone loss and falls. Some bad habits can increase your risk of osteoporosis. Important: The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, blogs, or WebMD Answers are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Until something happens, the disease doesn't make them feel bad, and the drug doesn't make them feel better. In: Isselbacher KJ, Braunwald E, Wilson JD et al, eds. We now have some excellent drugs for bone loss. vibramycin

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In patients requiring dental procedures, no data are available to suggest whether discontinuance of therapy prior to procedure reduces the risk of osteonecrosis of the jaw. 112 117 Base management of patients requiring dental treatment on an individual assessment of risks and benefits. It's used for the treatment of men and postmenopausal women who have severe and who are at high risk for bone fracture. Fosamax, none developed jaw osteonecrosis. This is used to treat certain types of and to increase bone mass. bones to become thinner and break more easily. This drug is available at a higher level co-pay. It appears that the risk is related to use of bisphosphonates for longer than five years. Height 5'4", 135 lbs. Generally active. Besides going to a gym to work out weight machines and aerobically 2-3 times a week, I take long hikes once a week and love to camp and take serious hikes in the wilderness several times a year. After 2 months on fosamax I started feeling pain in my thighs. I've experienced muscle pain and sciatica, and this was a different feeling. It really did feel like bone pain. For a while, I ignorantly attributed the pain to taking antihistamines, as someone told me they dehydrated your body and could cause leg pain. On the third month, I was LITERALLY hobbling to the bathroom in the morning - as opposed to my normally strong strides. I tried hiking with my husband on the beach, and I was so weak even he couldn't understand it. I cannot stress enough how much PAIN my legs felt, especially when I was relaxing. It was horrible pain. Then in the third month, I quit taking fosamax because the pain in my legs moved to my hips. I literally could NOT lie on my side in bed anymore - it hurt too much. I could last in that position for less than a minute. Seriously. After quitting fosamax, it took about a year for the pain in my pelvic area and hips and legs to subside. It's still not totally gone, but as of ONE YEAR after quitting fosamax, I can now lie on my side for a pretty extended period of time. It's not the same as before though. My legs occasionally get that old twang of pain, which can last awhile, when I'm relaxing to watch TV for example. My doctors now say I'm allergic to fosamax. I had trouble having any doctors take me seriously on this issue. It's been a tough time for me with fosamax. Wallach S, Cohen S, Reid DM et al. Effects of risedronate treatment on bone density and vertebral fracture in patients on corticosteroid therapy. Calcif Tissue Int. McClung M, Clemmesen B, Daifotis A et al. Alendronate prevents postmenopausal bone loss in women without osteoporosis: a double-blind, randomized, controlled trial. Ann Intern Med. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Ask your health care provider any questions you may have about how to use Fosamax. Levy RM, Keller M et al. Risedronate therapy prevents corticosteroid-induced bone loss: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis Rheum. The condition, sometimes called jawbone death, occurs when bone in the jaw fails to heal after a minor trauma. It results in pain, swelling, infection, and exposed bone. Thyroid problems. Too much thyroid hormone can cause bone loss. This can occur if your thyroid is overactive or if you take too much thyroid hormone medication to treat an underactive thyroid. Avoid excessive alcohol. Consuming more than two alcoholic drinks a day may decrease bone formation. Being under the influence of alcohol also can increase your risk of falling. Alendronate incorporates into bone and selectively inhibits osteoclast-mediated bone resorption in a dose-dependent manner. fluticasone

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Eating disorders. Severely restricting food intake and being underweight weakens bone in both men and women. Some people taking alendronate may have serious jawbone problems. Your doctor should check your mouth before you start this medication. Tell your dentist that you are taking this medication before you have any dental work done. To help prevent jawbone problems, have regular dental exams and learn how to keep your teeth and gums healthy. If you have jaw pain, tell your doctor and dentist right away. Three-character codes are assigned only in situations when more than one reference listed drug of the same strength has been designated under the same heading. Two or more reference listed drugs are generally selected only when there are at least two potential reference drug products which are not bioequivalent to each other. If a study is submitted that demonstrates bioequivalence to a specific listed drug product, the generic product will be given the same three-character code as the reference listed drug it was compared against. No dosage adjustment required. Fosamax Plus D is to be used only by the patient for whom it is prescribed. Do not share it with other people. So who's at risk of vitamin D deficiency? Be careful not to accidentally double dose -- acetaminophen may be one of the ingredients in other medicines you take. According to the FDA, there are over 600 medicines, both prescription and OTC, that contain this drug, including several medicines. Calcium or iron supplements, vitamins, antacids, coffee, tea, soda, mineral water, calcium-enriched juices, and food can decrease the absorption of alendronate. Do not take these for at least 30 minutes preferably 1 to 2 hours after taking alendronate. Shane E, Burr D, Ebeling PR et al. Atypical subtrochanteric and diaphyseal femoral fractures: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. Safety labeling change and REMS notification. Silver Spring, MD; 2010 Oct 13. From FDA website. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; black, tarry, or bloody stools; chest pain; coughing or vomiting blood; difficult or painful swallowing; mouth sores; new, worsening, or persistent heartburn; red, swollen, blistered, or peeling skin; severe bone, muscle, or joint pain especially in the hip, groin, or thigh; severe or persistent sore throat or stomach pain; swelling of the hands, legs, or joints; swelling or pain in the jaw; symptoms of low blood calcium eg, spasms, twitches, or cramps in your muscles; numbness or tingling in your fingers, toes, or around your mouth. Swallow Fosamax whole. Do not break, crush, chew, or suck on the tablet before swallowing. Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant. If you have any unusual effects, contact your doctor or promptly. But these events are more common in patients taking bisphosphonates than in patients taking other drugs. Take Fosamax Plus D by mouth on an empty stomach in the morning at least 30 minutes before your first food, drink, or other medicine of the day. Do NOT take Fosamax Plus D at bedtime or before you get out of bed in the morning.

Important information

When was that last bone density test? Other glands. Osteoporosis has also been associated with overactive parathyroid and adrenal glands. But the panel backed off giving any specific time limits. Do not share this medication with others. Dr. Paula Rackoff, assistant chief of rheumatology and director of the Osteoporosis Center at Beth Israel Medical Center in New York City. Cleveland Clinic: "Temporomandibular Disorders. Have you taken corticosteroid medications prednisone, cortisone as pills, injections or creams? This may not be a complete list of all interactions that may occur. Ask your health care provider if Fosamax Plus D may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. Do not consider Communities as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Protein is one of the building blocks of bone. And while most people get plenty of protein in their diets, some do not. Vegetarians and vegans can get enough protein in the diet if they intentionally seek suitable sources, such as soy, nuts, legumes, and dairy and eggs if allowed. Older adults may also eat less protein for various reasons. Protein supplementation is an option. should lexapro

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Wysowski DK, Chang JT. Alendronate and risedronate: reports of severe bone, joint, and muscle pain. Arch Intern Med. Paul Miller, MD, medical director of the Colorado Center for Bone Research, noted that long-term use wasn't an issue when bisphosphonates first came on the market. Safety and effectiveness of Hycodan in pediatric patients under six have not been established. Now I'm sitting at my desk and I have horrible pain in between my shoulders radiating down my spine. It's obviously the med. I'm calling my doc and asking for something else. This is scary for me because when my grandmother passed away, she was so hunched over, her spine had to be broken in order for her to fit into the coffin. The thought of that is upsetting. I work in the nursing field and have witnessed first hand how a fracture alters ones quality of life. It affects both the physical and mental being. Use Fosamax Plus D as directed by your doctor. Check the label on the medicine for exact dosing instructions. How is your diet, especially dairy intake? Calcium gluconate and calcium lactate. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fosamax Plus D while you are pregnant. Fosamax Plus D is found in breast milk. If you are or will be breast-feeding while you use Fosamax Plus D, check with your doctor. Discuss any possible risks to your baby. Skelid and zoledronic acid Reclast, Zometa. 2008 Nov 12. Available from FDA website. How can you get enough calcium and vitamin D in your daily diet? Follow the diet and exercise program given to you by your health care provider. Combine strength training exercises with weight-bearing and balance exercises. Therapeutic Research Faculty 2009. Stomach pain, constipation, diarrhea, gas, or nausea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Continue alendronate as long as patient continues to receive corticosteroid therapy. Long-term use of oral or injected corticosteroid medications, such as prednisone and cortisone, interferes with the bone-rebuilding process. canada and augmentin

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Fosamax is in a class of drugs that strengthen bone. Bone is in a constant state of remodeling, whereby old bone is removed by cells called osteoclasts, and new bone is laid down by cells called osteoblasts. Thacker, who was not involved in the study, notes that Watts and colleagues looked at the kind of women doctors see in real life. Moreover, they evaluated the endpoint that really matters to women suffering bone loss -- actual bone fractures. There are so many types of over-the-counter OTC remedies to choose from, though -- and each one helps relieve pain in its own way. Make a note of key personal information, including things like recent life changes, or major stresses. It freaked me out! Bone is living tissue that is constantly being broken down and replaced. Osteoporosis occurs when the creation of new bone doesn't keep up with the removal of old bone. Food and Drug Administration. Solomon DH, Patrick A, Brookhart MA. More on reports of esophageal cancer with oral bisphosphonate use. N Engl J Med.

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Is it possible that you have something completely different going on in your back? Here's some information to help you get ready for your appointment, and what to expect from your doctor. If you are taking the chewable tablet or wafers, chew the medication thoroughly before swallowing. not swallow whole wafers. Fosamax Plus D may cause jawbone problems in some patients. Your risk may be greater the longer you take Fosamax Plus D or if you have cancer, poor dental hygiene, ill-fitting dentures, or certain other conditions eg, anemia, blood clotting problems, dental problems, infection. Your risk may also be greater if you have certain dental procedures or you use certain medicines or therapies eg, chemotherapy, corticosteroids, radiation. plaquenil overseas

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Committee on Educational Bulletins of the American College of Obstetricians and Gynecologists. ACOG Educational Bulletin: osteoporosis. Obstet Gynecol. Health Care Financing Administration. Medicare program; medicare coverage of and payment for bone mass measurements. 42 CFR Part 410. Interim rule. Fed Regist. FDA advisory panel voted today.

During this time, bone mass is lost faster

Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. voltaren

Do I need to be screened for osteoporosis?

Do I need to be screened for osteoporosis? Eastell R. Treatment of postmenopausal osteoporosis. N Engl J Med. Used alone or in fixed combination with cholecalciferol for treatment of osteoporosis in men. Gastrointestinal surgery. Surgery to reduce the size of your stomach or to remove part of the intestine limits the amount of surface area available to absorb nutrients, including calcium. Side Effects List Fosamax Tablet side effects by likelihood and severity. torsemide

Is alendronate available as a generic drug? Bisphosphonates. These include ibandronate Boniva risedronate and Reclast. Intravenous increases blood levels of alendronate. That research failed to find a significant increase in esophageal cancer risk in users of the drugs. American College of Rheumatology Ad Hoc Committee on Glucocorticoid-induced Osteoporosis. Recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis: 2001 update. Arthritis Rheum. levothyroxine buy store uk

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